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Does inflammation contribute to premenstrual symptoms?

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Women with premenstrual symptoms (PMS) including mood swings, weight gain/bloating, and abdominal cramps/back pain have elevated levels of C-reactive protein (CRP), a biomarker of inflammation associated with increased risk of cardiovascular disease. Establishing a link between inflammation and PMS would have important implications for treatment and prevention using anti-inflammatory agents and for cardiovascular disease risk reduction, according to an article in Journal of Women's Health.

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